Luteolin Luteolin 98% Test by HPLC
2022-01-18 09:32
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Luteolin, a polyphenolic plant flavonoid, has been attributed with numerous beneficial properties like anti-cancer, antioxidant, and anti-inflammatory action. Luteolin has been reported earlier to be neuroprotective in models of spinal cord injury and traumatic brain injury and also induces neurite outgrowth in PC12 cells. However, the effect of luteolin on early differentiation, which might be important for its beneficial effects, is unknown. In this report, we show that luteolin negatively affects early differentiation of embryonic stem cells, hampering the formation of embryoid bodies. At later stages of differentiation, luteolin specifically inhibits neuronal differentiation, where the expression of early neuronal markers is suppressed, whereas luteolin treatment does not inhibit expression of meso- and endodermal markers. Further, in a developing zebrafish model, luteolin treatment leads to fewer numbers of mitotic cells in the brain. These specific effects of luteolin on neuronal differentiation could possibly be due to its ability to inhibit the lysine acetyltransferase, p300, since the structurally closely related p300 non-inhibitor flavonoid, apigenin, does not inhibit neuronal differentiation. These results show that luteolin perturbs neuronal differentiation of embryonic stem cells.
Description:
Product name: luteolin powder
Latin name:Arachis hypogaea
Active ingredient: luteolin
Part used: Shell
Assay:98%
Appearance:Yellow Needle Powder
Test method: HPLC
Introduction:
Luteolin is a naturally occurring molecule known as bioflavonoid, often found in foods including parsley, artichoke leaves, celery, peppers, olive oil, rosemary, lemons, peppermint, sage, thyme, and many others. Luteolin is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an agent in the prevention of inflammation, a promoter of carbohydrate metabolism, and an immune system modulator.
Function
1. Luteolin has the function of anti-inflammatory, anti-microbial and anti-virus.
2. Luteolin has anti-tumor effect. Especislly having a good inhibition on prostate cancer and breast cancer.
3. Luteolin has the function of relaxating and protecting vascular
4. Luteolin can reduce the level of hepatic fibrosis and protect liver ce
Application
1. Applied in food field, Luteolin is often used as food additives.
2. Applied in health product field, Luteolin is made into capsules with the function of vasodilatation.
3. Applied in pharmaceutical field, Luteolin can play the role of inflammation.
4. Applied in cosmetic field, Luteolin is often made into the products of losing weight.
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